Since Magufuli was elected in 2015, Lissu has made it his job to fearlessly challenge the autocratic leader - and more than a dozen bullet wounds were not enough to shut him up.
Almost three years ago, Lissu, the former president of the Tanganyika Law Society (TLS), was en route to his home in Tanzania's capital Dodoma at around 11am for a lunch break during a parliamentary session.
The changes to Tanzanian society were "immediate" following Magufuli's election win almost five years ago, Lissu says.
According to Lissu, Magufuli, quite simply, needs the money to implement dozens of national megaprojects he has spearheaded, while Magufuli's fledgling attempts at revamping Air Tanzania, the country's flag carrier, have alone cost hundreds of millions of dollars.
What's unique under Magufuli, according to Lissu, is that the arrests are being made solely for criticising the president.