Analysis - Almost 18 months into the COVID-19 pandemic, the release of new case numbers is an integral part of the day for many South Africans. Questions like "When will the third wave end?" and "Will there be a fourth wave?" abound and opinions, even among experts, are varied. The challenges in interpreting COVID-19 case and hospitalisation data are enormous. They are likely to become even more complex as SARS-CoV-2 vaccine coverage is added to the epidemiological mix. The Conversation Africa asked three experts who