Henry Jay Lewis, musician and conductor, was born October 16, 1932 in Los Angeles to automobile dealer Henry J. Lewis, and nurse Mary Josephine Lewis. Lewis started playing the piano when he was five, and in junior high he learned to play the double bass while also studying voice, clarinet, and other instruments. His talent playing the double bass earned him a scholarship to attend the University of Southern California.

Lewis married accomplished white opera singer Marilyn Horne in 1960 and they had daughter Angela in 1965. The two divorced in 1974. Lewis and Horne often appeared in magazines and newspapers in articles focusing both on their musical accomplishments and on their interracial relationship.

Lewis became the youngest and first black instrumentalist in a major American orchestra when he joined the Los Angeles Philharmonic Orchestra in 1948 at age 16.  Lewis was drafted into the army in 1954, and he conducted the Seventh Army Symphony based out of Germany until his discharge in 1957.

Lewis broke racial barriers in the American field of conducting, becoming the first African American to serve as conductor and musical director of a major American orchestra (the New Jersey Symphony) in 1968, and the first African American to conduct the Metropolitan Opera, in 1972.

During his eight years as conductor and musical director, Lewis build the Newark-based  New Jersey Symphony Orchestra into a first-class orchestra with a 100-concert season, over $1 million budget, and appearances at prestigious venues such as Carnegie Hall and the Kennedy Center among others. Lewis also expanded the outreach of the Orchestra into some of New Jersey’s poorest neighborhoods, often selling seat tickets for as little as $1 to encourage a broad audience. Lewis left his position at the Orchestra on rocky terms, however, after members accused him of being tyrannical.

Lewis then spent the next two decades guest-conducting abroad, leading orchestras in Milan, Italy, London, England, Paris, France, Tokyo, Japan, and Copenhagen,